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Metabolic dysfunction-associated steatohepatitis (MASH) is a significant public health concern. Two reasons set the alarm: an estimated global prevalence of 5.27% and a lack of approved pharmacological treatments.  Among [...]

Primary human hepatocytes vs. cell lines in researh . Understanding the distinction between primary cells vs cell lines is essential for selecting the appropriate in vitro model in biomedical [...]

Isolation and culture of human primary hepatocytes   Primary human hepatocytes are considered the gold standard for liver cell studies due to their ability to closely mimic the physiological [...]

How are HepG2 cells different from primary hepatocytes? Cellular models can make all the difference in biomedical research. In particular, the liver's complex functions require models that accurately reflect [...]

Predictive genotoxicity and mutagenicity of drugs using liver-on-a-chip Liver-on-a-chip (LOC) models are increasingly recognized as a powerful tool in drug development. These models replicate the complex environment of the [...]

In vitro lung models for translational research in respiratory diseases The COVID-19 pandemic highlighted the need for reliable lung in vitro models to efficiently respond to an emergency by [...]