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Human biospecimens are essential for preclinical research, but their value goes beyond their biological origin. Sample handling, storage, and transport impacts on their quality and, therefore, on the reliability [...]

Human biospecimens are a critical input for preclinical research, but their scientific value is highly dependent on how they are handled throughout their lifecycle. Variability introduced during collection, processing, [...]

Cryopreserved primary human liver cells offer a practical balance between biological relevance and operational efficiency. When handled correctly, cryopreserved hepatocytes and non-parenchymal cells (NPCs) retain key metabolic, transporter, and [...]

22% of clinical trials fail due to hepatotoxicity, and the number rises to 32% when talking about market withdrawals. These figures highlight a persistent gap in our ability to [...]

What Are Liver Non‑Parenchymal Cells and How Do They Differ from Hepatocytes? Liver non-parenchymal cells (NPCs) are a heterogeneous group of cells that form the non-hepatocyte component of the [...]

Hepatocytes represent 70% of the liver cells, which underscores their essential role in liver function. Hepatocytes play a key role in metabolism, detoxification, and regeneration. Their unique structure and [...]