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Cryopreserved primary human liver cells offer a practical balance between biological relevance and operational efficiency. When handled correctly, cryopreserved hepatocytes and non-parenchymal cells (NPCs) retain key metabolic, transporter, and [...]

22% of clinical trials fail due to hepatotoxicity, and the number rises to 32% when talking about market withdrawals. These figures highlight a persistent gap in our ability to [...]

What Are Liver Non‑Parenchymal Cells and How Do They Differ from Hepatocytes? Liver non-parenchymal cells (NPCs) are a heterogeneous group of cells that form the non-hepatocyte component of the [...]

Hepatocytes represent 70% of the liver cells, which underscores their essential role in liver function. Hepatocytes play a key role in metabolism, detoxification, and regeneration. Their unique structure and [...]

Types of hepatocytes: A comprehensive guide for researchers . Hepatocytes, the primary functional cells of the liver, are essential for various applications in research, including drug metabolism, toxicology, and [...]

Metabolic dysfunction-associated steatohepatitis (MASH) is a significant public health concern. Two reasons set the alarm: an estimated global prevalence of 5.27% and a lack of approved pharmacological treatments.  Among [...]