Primary Human Hepatic Stellate Cells

Human hepatic stellate cells (HSCs) are liver-specific mesenchymal cells located in the space of Disse, between the endothelial cells of the sinusoid and the hepatocytes. Stellate cells are the main cell type involved in liver fibrosis in response to liver injury, and play a key role in liver extracellular matrix homeostasis, repair, regeneration and fibrosis, and control retinol metabolism, storage and release.

In their quiescent state, human hepatic stellate cells contain numerous lipid droplets of vitamin A, which constitute the largest reservoir of vitamin A in the body. In addition, human hepatic stellate cells have the ability to switch to their activated state and transdifferentiate into myofibroblast-like cells, which are involved in the pathogenesis of liver fibrosis.

Ref. Product Packaging
HuSC-P1 Stellate cells, passage 1 100.000
HuSC-P2 Stellate cells, passage 2 100.000
HuSC-P3 Stellate cells, passage 3 100.000
HuSCP  Plated Stellate cells  1 plate

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