Primary Human Hepatic Stellate Cells

Human Hepatic stellate cells (HSCs) are liver-specific mesenchymal cells and are located in the space of Disse, between endothelial cells of the sinusoid and hepatocytes. These cells are the major cell type involved in liver fibrosis in response to liver injury, and they play a key role in the homeostasis of liver extracellular matrix, repair, regeneration and fibrosis, and control retinol metabolism, storage and release.

In their quiescent state, Human Hepatic stellate cells contain numerous vitamin A lipid droplets, constituting the largest reservoir of vitamin A in the body. Besides, Human Hepatic stellate cells has the capability to change into their activated stage transdifferentiating into myofibroblast-likecells which are linked with the pathogenesis of hepatic fibrosis.

Ref. Product Packaging
HuSC-P1 Stellate cells, passage 1 100.000
HuSC-P2 Stellate cells, passage 2 100.000
HuSC-P3 Stellate cells, passage 3 100.000
HuSCP  Plated Stellate cells  1 plate

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