Human Endothelial Cells

The liver contains two distinct endothelial cell types: vascular (LEC) and sinusoidal (LSEC).

Liver sinusoidal human endothelial cells (LSECs) are specialized endothelial cells with high permeability and capacity for endocytosis, which line the sinusoid and separate the blood cells from the hepatocytes and stellate cells.

Liver human endothelial cells (LEC) and Liver Endothelial sinusodial cells (LSEC) represent the primary permeable barrier in blood vessels making them highly dynamic cells that regulate the passage of substances between the bloodstream and liver tissue.

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Ref.	Product	Packaging
HuLEC/LSEC-P1	Liver endothelial & sinusoidal cells (LEC – LSEC) passage 1	100.000 500.000
HuLEC/LSEC-P1	Liver endothelial & sinusoidal cells (LEC – LSEC) passage 2	100.000 500.000
HuLEC/LSEC-P1	Liver endothelial & sinusoidal cells (LEC – LSEC) passage 2	100.000 500.000

Inventary

ENDOTHELIAL AND SINUSOIDAL ENDOTHELIAL CELLS STOCK Use filters on the table to find the best lot for your needs. Use the "export option" in the top right corner to export data (it can be exported table by table (excel) or all together (PDF, HTML)). See videos below for further information. For requests or further information about Cytes Biotechnologies primary Human Liver Endothelial and Sinusoidal Cells (Contact us)

Product Details

Endothelial cells also contribute to the immune response within the liver. They express dhesion molecules and receptors that facilitate the recruitment and interaction of immune cells, such as Kupffer cells and lymphocytes, during infection or inflammation. Moreover, liver endothelial cells participate in the metabolism and detoxification of drugs and xenobiotics by expressing various drug-metabolizing enzymes.

They play vital roles in regulating blood flow, nutrient exchange, immune responses, and fibrosis. Further research into the biology and functions of these cells is crucial for advancing our knowledge of liver physiology and developing targeted therapies for liver diseases.

Human endothelial cells and human endothelial sinusoidal cells Characterization

Basic Characterization

Cell number and viability after thawing
Morphological analysis of cells over time

Advanced Characterization II

The principal markers present in the Human endothelial cells and human endothelial sinusoidal cells are used to determine their expression and percentage

Common Uses

In-vitro toxicity testing
Clearance of pathogens and macromolecules
Liver Regeneration

Documentation

Human endothelial cells and human endothelial sinusoidal cells are produced under rigorous QC standards and supplied with:

Demographic and clinical donor profile
Viability and morphology assessment
Specific COA with culture and maintenance protocols
Specific LEC/LSEC media

Endothelial and Sinusoidal Cells Culture Protocol

CHM2210-LEC-LSEC-p1-Z CoA

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Shipping
We avoid shipments arriving at weekends or holidays.
We store and ship all cell products at the most favorable temperature range for the product, and we monitor the safety and integrity of shipped products proactively.
All of our products are delivered in compliance of the IATA Dangerous Goods Regulations.

Shipping conditions: Dry ice (-80ºC)/ LN (-196ºC)

Packaging
Packaging and shipping fresh products to preserve its quality when transporting, to ensure that all primary cell products are protected with integrity and viability.
Leak-proof packaging materials that meet the general requirements of carriers and customs authorities, where applicable usually ship at room temperature.