Human Liver Endothelial Cells
The two types of endothelial liver cells are vascular (LEC) and sinusoidal (LSEC).
Human hepatic sinusoidal endothelial cells (LSECs) are specialized liver endothelial cells with high permeability and endocytosis capacity, which line the sinusoid and separate blood cells from hepatocytes and stellate cells.
Ref. | Product | Packaging |
---|---|---|
HuLEC/LSEC-P1 | Liver endothelial & sinusoidal cells (LEC – LSEC) passage 1 | 100.000 500.000 |
HuLEC/LSEC-P1 | Liver endothelial & sinusoidal cells (LEC – LSEC) passage 2 | 100.000 500.000 |
HuLEC/LSEC-P1 | Liver endothelial & sinusoidal cells (LEC – LSEC) passage 2 | 100.000 500.000 |
Liver endothelial cells also contribute to the immune response within the liver. They express adhesion molecules and receptors that facilitate the recruitment and interaction of immune cells, such as Kupffer cells and lymphocytes, during infection or inflammation. In addition, liver endothelial cells participate in the metabolism and detoxification of drugs and xenobiotics by expressing various drug-metabolizing enzymes.
Liver endothelial cells play vital roles in the regulation of blood flow, nutrient exchange, immune responses and fibrosis. Continuing to investigate the biology and functions of these cells is crucial to advance our understanding of liver physiology and to develop targeted therapies for liver diseases.
Human endothelial cells and human endothelial sinusoidal cells Characterization
Basic Characterization
- Cell number and viability after thawing
- Morphological analysis of cells over time
- Advanced Characterization II
The main markers present in human liver endothelial cells and human sinusoidal endothelial cells are used to determine their expression and percentage.
Common Uses
- In-vitro toxicity testing
- Clearance of pathogens and macromolecules
- Liver Regeneration
Human endothelial cells and human endothelial sinusoidal cells are produced under rigorous QC standards and supplied with:
- Demographic and clinical donor profile
- Viability and morphology assessment
- Specific COA with culture and maintenance protocols
- Specific LEC/LSEC media
Shipping
We avoid shipments arriving at weekends or holidays.
We store and ship all cell products at the most favorable temperature range for the product, and we monitor the safety and integrity of shipped products proactively.
All of our products are delivered in compliance of the IATA Dangerous Goods Regulations.
Shipping conditions: Dry ice (-80ºC)/ LN (-196ºC)
Packaging
Packaging and shipping fresh products to preserve its quality when transporting, to ensure that all primary cell products are protected with integrity and viability.
Leak-proof packaging materials that meet the general requirements of carriers and customs authorities, where applicable usually ship at room temperature.
Related Products
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