Liver models to test new drugs based on 2D cell culture of primary hepatocytes and the use of experimental animal models are slow, costly, and have significant biases. BeCytes [...]
Drug-induced liver injury (DILI) has fatal consequences, both personally and economically. Its health impact ranges from mild liver enzyme elevation to severe liver failure. In the drug development process, [...]
Regulatory agencies, such as the Food and Drug Administration (FDA), are moving towards reducing animal testing and encouraging the use of New Alternative Methodologies (NAMs) in pharmaceutical research. NAMs [...]
Experts talks: In vitro liver models for reliable predictions in preclinical stages The advent of new alternative methodologies marks a significant stride forward in biomedical research, enabling safer and [...]
Organoids vs Spheroids: 3 important differences The evolution from 2D monolayer cultures towards 3D cell cultures has marked a crucial advance for modeling human development and diseases. Since the [...]
Human hepatic stellate cells (HSCs) are liver-specific mesenchymal cells located in the space of Disse, between the endothelial cells of the sinusoid and the hepatocytes. Although HSCs represent only 5–10% [...]
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Cytes Biotechnologies S.L. within the framework of the Export Initiation Program of ICEX, has had the support of ICEX and with the co-financing of the European FEDER fund. The purpose of this support is to contribute to the international development of the company and its environment.
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