About Us
BeCytes Biotechnologies
Who We Are
BeCytes Biotechnologies is a biotechnological company that offers products and CRO services based on tissue procurement, cell isolation and cell solutions for in vitro models addressed to the research community worldwide. Our main area of expertise is the production of primary liver cells from human and animal origin.
Furthermore, BeCytes Biotechnologies has created a platform capable of coordinating the donation of human tissues and cells for biomedical research purposes, which encompasses strong collaborations with national and international procurement centers.
Our Mission
At BeCytes Biotechnologies, our mission is to empower and support researchers by providing high-quality primary cells, tissue sourcing services, and expert support. We are dedicated to accelerating scientific advancements while ensuring excellence at every step of the process.
Our Vision
Our vision likely revolves around becoming a leading global provider of innovative and reliable biotechnological solutions that enhance biomedical research, drive successful preclinical development activities, and contribute to the discovery of transformative therapies for human health.
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Collaborative Projects
This international project, which accounts for more than 50 partners kicked off in May 2024, aims to develop, optimize, and validate Organ-on-Chips (OOC) technologies for different organs to replace the need for animal and in-human testing in drug discovery, clinical testing, and validation.
To unlock organ-on-a-chip’s true potential, we need to advance in automation, reproducibility, scalability, and standardization and put them into a format that makes them accessible for broader use in industry and academia.
BeCytes Biotechnologies will establish a robust network of hospitals to facilitate the collection of human lung and blood samples. The objective will be to isolate and characterize lung cells and PBMCs from the same donors for the creation of the biological models.
This project is supported by the Chips Joint Undertaking and its members Belgium, Germany, Hungary, Ireland, Italy, the Netherlands, Portugal, Romania, Spain, Switzerland. This work includes top-up funding from the Swiss State Secretariat for Education, Research and Innovation (SERI).
NUCLIS – Bioprinted in vitro liver models to propel clinical advances in drug development
Liver models to test new drugs based on 2D cell culture of primary hepatocytes and the use of experimental animal models are slow, costly, and have significant biases.
BeCytes Biotechnologies, in collaboration with the Biosensors for Bioengineering group, led by Javier Ramón from the Institute for Bioengineering of Catalonia (IBEC), aims to create cutting-edge 3D in vitro human liver models using diverse human hepatic cells by bio-printing.
These models represent a valuable alternative to poor predictive 2D models and a tool to refine the drug development process by reducing animal experimentation complying with the 3Rs principle.
The Nuclis I+D project “Generation of new 3D models of microencapsulated liver cell pools by bioprinting”, funded by Agència per la Competitivitat de l’Empresa (ACCIÓ), kicked off in February 2023 and promises to revolutionize liver research. This project is an excellent example of public and private collaboration between a TECNIO center, IBEC, and an innovative company such as BeCytes Biotechnologies.
BeCytes Publications
- Busche, M., Tomilova, O., Schütte, J., Werner, S., Beer, M., Groll, N., Hagmeyer, B., Pawlak, M., Jones, P. D., Schmees, C., Becker, H., Schnabel, J., Gall, K., Hemmler, R., Matz-Soja, M., Damm, G., Beuck, S., Klaassen, T., Moer, J., … Stelzle, M. (2020). HepaChip-MP – a twenty-four chamber microplate for a continuously perfused liver coculture model. Lab on a Chip, 20(16), 2911–2926. https://doi.org/10.1039/D0LC00357C
- Lomba, L., Garralaga, M. P., Werner, Á., Giner, B., Baptista, P. M., & Sánchez-Romero, N. (2023). Ibuprofen solubility and cytotoxic study of deep eutectic solvents formed by xylitol, choline chloride and water. Journal of Drug Delivery Science and Technology, 82, 104327. https://doi.org/10.1016/J.JDDST.2023.104327
- Pla-Palacín, I., Sánchez-Romero, N., Morini, S., Rubio-Soto, D., Baptista, P.M. (2021). Liver Tissue Engineering. In: Eberli, D., Lee, S.J., Traweger, A. (eds) Organ Tissue Engineering. Reference Series in Biomedical Engineering(). Springer, Cham.: https://doi.org/10.1007/978-3-030-44211-8_2
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